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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CSNK2A1 All Species: 36.06
Human Site: Y261 Identified Species: 49.58
UniProt: P68400 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P68400 NP_001886.1 391 45144 Y261 L Y D Y I D K Y N I E L D P R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001112211 397 46613 Y261 L Y D Y I D K Y N I E L D P R
Dog Lupus familis XP_534375 403 46681 Y261 L Y D Y I D K Y N I E L D P R
Cat Felis silvestris
Mouse Mus musculus Q60737 391 45143 Y261 L Y D Y I D K Y N I E L D P R
Rat Rattus norvegicus P19139 391 45055 Y261 L Y D Y I D K Y N I E L D P R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507666 350 41142 F234 I F R K E P F F H G Q D N Y D
Chicken Gallus gallus P21868 391 45172 Y261 L Y D Y I D K Y N I E L D P R
Frog Xenopus laevis P28020 392 45169 Y261 L Y D Y I D K Y N I E L D P R
Zebra Danio Brachydanio rerio NP_001002164 393 45422 Y261 L Y D Y I D K Y N I E L D P R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P08181 336 39941 A221 W S L G C M L A S M I F R K E
Honey Bee Apis mellifera XP_393260 350 41645 P229 S M I F R K E P F F H G H D N
Nematode Worm Caenorhab. elegans P18334 360 42239 I244 N Y D Q L V R I A K V L G T D
Sea Urchin Strong. purpuratus XP_785475 398 46271 Y259 L Y E Y L D K Y Q I E L D P R
Poplar Tree Populus trichocarpa
Maize Zea mays P28523 332 39212 F217 M W S L G C M F A G M I F R K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q08467 333 39240 A218 W S L G C M F A G M I F R K E
Baker's Yeast Sacchar. cerevisiae P19454 339 39385 L224 L N Q Y D Y S L D L W S V G C
Red Bread Mold Neurospora crassa Q8TG13 336 39621 R221 M F A S M I F R K E P F F H G
Conservation
Percent
Protein Identity: 100 N.A. 90.4 97 N.A. 97.4 98.4 N.A. 75.4 97.9 94.9 89 N.A. 75.9 79.5 72.8 78.3
Protein Similarity: 100 N.A. 92.1 97 N.A. 98.7 98.9 N.A. 82.6 98.9 97.1 93.8 N.A. 81.8 86.1 82.3 87.1
P-Site Identity: 100 N.A. 100 100 N.A. 100 100 N.A. 0 100 100 100 N.A. 0 0 20 80
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. 40 100 100 100 N.A. 13.3 13.3 33.3 93.3
Percent
Protein Identity: N.A. 65.2 N.A. 63.4 49.8 61.1
Protein Similarity: N.A. 74.9 N.A. 75.4 63.6 72.8
P-Site Identity: N.A. 0 N.A. 0 13.3 0
P-Site Similarity: N.A. 33.3 N.A. 6.6 26.6 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 6 0 0 0 0 12 12 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 12 6 0 0 0 0 0 0 0 0 6 % C
% Asp: 0 0 53 0 6 53 0 0 6 0 0 6 53 6 12 % D
% Glu: 0 0 6 0 6 0 6 0 0 6 53 0 0 0 12 % E
% Phe: 0 12 0 6 0 0 18 12 6 6 0 18 12 0 0 % F
% Gly: 0 0 0 12 6 0 0 0 6 12 0 6 6 6 6 % G
% His: 0 0 0 0 0 0 0 0 6 0 6 0 6 6 0 % H
% Ile: 6 0 6 0 48 6 0 6 0 53 12 6 0 0 0 % I
% Lys: 0 0 0 6 0 6 53 0 6 6 0 0 0 12 6 % K
% Leu: 59 0 12 6 12 0 6 6 0 6 0 59 0 0 0 % L
% Met: 12 6 0 0 6 12 6 0 0 12 6 0 0 0 0 % M
% Asn: 6 6 0 0 0 0 0 0 48 0 0 0 6 0 6 % N
% Pro: 0 0 0 0 0 6 0 6 0 0 6 0 0 53 0 % P
% Gln: 0 0 6 6 0 0 0 0 6 0 6 0 0 0 0 % Q
% Arg: 0 0 6 0 6 0 6 6 0 0 0 0 12 6 53 % R
% Ser: 6 12 6 6 0 0 6 0 6 0 0 6 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 6 0 % T
% Val: 0 0 0 0 0 6 0 0 0 0 6 0 6 0 0 % V
% Trp: 12 6 0 0 0 0 0 0 0 0 6 0 0 0 0 % W
% Tyr: 0 59 0 59 0 6 0 53 0 0 0 0 0 6 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _